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CT Head With Contrast

CT+ ContrastNeuro
Indications
  • Suspected intracranial mass or metastasis (when MRI unavailable/contraindicated)
  • Suspected infection/abscess, empyema, meningitis complications
  • Follow-up of known tumor, postoperative tumor bed
  • Suspected dural venous sinus thrombosis (often CT venography)
  • Vascular lesion evaluation when MRI not feasible
Patient prep
  • Screen renal function/eGFR per institutional contrast policy; document contrast allergy and premedicate if indicated
  • IV access (typically 20-22 G)
  • No routine NPO, though many sites hold solids ~2-4 h for contrast
  • Remove metallic objects from field; position supine head-first in head holder
Contrast
Agentiodinated (e.g. iohexol 350 or iopamidol 370)
RouteIV
Dose≈70-100 mL at 1.5-3 mL/s
TimingPost-contrast acquisition at ~60-90 s delay (parenchymal/equilibrium); for CTV ~45-60 s
Technique
  • Supine, head first; coverage foramen magnum to vertex
  • Often paired with a non-contrast series for comparison depending on indication
  • 120 kV; mAs per scanner with AEC; iterative reconstruction
  • Reconstruct soft-tissue 4-5 mm axial plus thin source for coronal/sagittal reformats; bone kernel if osseous involvement
  • No breath-hold required
Series / Sequences
#Series / SequencePlaneThicknessNotes
1Axial post-contrast (soft tissue)axial4-5 mmBrain window; evaluate enhancement
2Coronal reformatcoronal2-3 mmFrom thin source
3Sagittal reformatsagittal2-3 mm
4Axial bone (optional)axial0.625-1.25 mmIf skull base/calvarial involvement suspected
Key points
  • MRI with contrast is generally preferred for tumor/infection; CT with contrast is a substitute when MRI is unavailable or contraindicated
  • Pre- and post-contrast comparison helps distinguish enhancement from hemorrhage/calcification
  • For suspected dural sinus thrombosis perform CT venography with venous-phase timing
  • Iodine load modest for head; balance opacification vs dose
References
• ACR–ASNR–SPR Practice Parameter for the Performance of CT of the Brain
• ACR Appropriateness Criteria: Headache; Neurologic Deficit
• Radiopaedia: CT brain with contrast link
• ACR Manual on Contrast Media
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.