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CT Pancreas (Dual-Phase Pancreatic Protocol)

CT+ ContrastAbdomen & Pelvis
Indications
  • Pancreatic adenocarcinoma detection and staging/resectability (vascular involvement)
  • Pancreatitis and complications; cystic pancreatic lesions (IPMN)
  • Neuroendocrine tumor evaluation
Patient prep
  • NPO 4 h
  • Water as neutral oral contrast to distend duodenum/stomach (avoid positive oral contrast that obscures vessels)
  • 18-20G IV; renal function check
  • Arms up
Contrast
Agentiodinated (iohexol 350 / iopamidol 370)
RouteIV (+ oral water)
Dose~1.5 mL/kg or 100-150 mL at 4-5 mL/s + saline chase
TimingPancreatic parenchymal/late-arterial phase ~40-45 s (peak gland enhancement, tumor conspicuity) and portal venous ~65-70 s (venous involvement, liver mets); non-contrast optional
Technique
  • Supine, arms up; coverage liver dome through pancreas/abdomen (pelvis if staging)
  • Neutral oral contrast (water) for duodenal distention
  • Bolus tracking; dual phase—pancreatic parenchymal (~40-45 s) and portal venous (~65-70 s)
  • 120 kV (100 kV thin); thin recon 0.75-3 mm
  • Curved/oblique reformats along SMA/SMV/celiac for vascular encasement; coronal reformats
Series / Sequences
#Series / SequencePlaneThicknessNotes
1Pancreatic parenchymal axialaxial0.75-3 mmPeak gland enhancement; tumor hypodensity, arterial involvement
2Portal venous axialaxial2.5-3 mmSMV/portal/splenic vein involvement, liver mets
3Curved MPR (vessels)obliquethinArterial/venous encasement (resectability)
4Coronal reformatcoronal2-3 mmDuctal/overview
Key points
  • Pancreatic (late arterial ~40-45 s) phase maximizes tumor-to-gland contrast; tumors are typically hypoenhancing
  • Report resectability per NCCN: arterial (celiac, SMA, CHA) and venous (SMV, PV) contact/encasement
  • Neutral oral water improves duodenal/ampullary and vascular assessment
  • Thin recon enables multiplanar vascular reformats
  • Look for secondary signs: ductal dilation, abrupt cutoff, parenchymal atrophy
References
• ACR-SAR-SPR Practice Parameter for CT of the Abdomen
• RadioGraphics / SAR-AGA consensus on pancreatic ductal adenocarcinoma CT reporting
• Radiopaedia: pancreatic CT protocol ( link
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.