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Meckel Diverticulum Scan (Tc-99m Pertechnetate)

NM+ ContrastAbdomen & Pelvis
Indications
  • Detection of ectopic gastric mucosa in Meckel diverticulum
  • Evaluation of painless lower GI bleeding, especially in children/young adults
Patient prep
  • Fast 4-6 hours (reduces gastric secretions/peristalsis)
  • Avoid recent barium studies (attenuation artifact)
  • Avoid recent in vivo Tc labeling / perchlorate
  • Pharmacologic enhancement optional: pentagastrin, H2 blocker (cimetidine/ranitidine pretreatment 1-2 days enhances retention), or glucagon
Contrast
AgentTc-99m pertechnetate (taken up by gastric mucosa)
RouteIV
DoseAdult ~10 mCi (370 MBq); pediatric weight-based ~50-100 uCi/kg
TimingDynamic/serial imaging immediately and for ~30-60 min
Technique
  • LEHR collimator, 140 keV, supine, abdomen/pelvis in FOV
  • Dynamic acquisition ~1 min/frame for 30-60 min
  • Anterior abdomen; lateral/oblique and post-void views to separate from bladder/ureter
  • Cimetidine premedication (blocks pertechnetate secretion, increases mucosal retention) improves sensitivity
Series / Sequences
#Series / SequencePlaneNotes
1Dynamic abdomen/pelvisAnterior1 min/frame x 30-60 min; focus appears synchronous with stomach
2Lateral / post-voidLateral / anteriorDistinguish ectopic mucosa from bladder/ureteral activity
Key points
  • Positive: focal uptake (usually RLQ) appearing and intensifying with the stomach
  • Cimetidine pretreatment enhances sensitivity by reducing pertechnetate washout from mucosa
  • False positives: GU activity, inflammation, intussusception; false negatives: small/no ectopic mucosa
  • Empty bladder to avoid masking pelvic lesions
References
• SNMMI Procedure Guideline for Meckel Diverticulum Scintigraphy
• Radiopaedia: Meckel scan link
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.