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MRI Abdomen / Liver With and Without Contrast + MRCP

MR+ ContrastAbdomen & Pelvis
Indications
  • Characterize liver lesion (HCC, mets, hemangioma, FNH, adenoma)
  • Cirrhosis screening / LI-RADS
  • Biliary obstruction / stones (MRCP)
  • Pancreaticobiliary evaluation
  • Iron/fat quantification
Patient prep
  • NPO ~4-6 hours (reduces bowel motion, improves MRCP, ensures GB distension)
  • MRI safety screening
  • IV access for contrast
  • Body/torso phased-array coil; breath-hold coaching
Contrast
Agentgadolinium-based; extracellular (e.g., gadobutrol) OR hepatobiliary (gadoxetate disodium/Eovist)
RouteIV
DoseExtracellular 0.1 mmol/kg; gadoxetate 0.025 mmol/kg (0.1 mL/kg)
TimingDynamic: arterial (~late arterial via bolus tracking), portal venous (~60-70 s), delayed (~3-5 min); hepatobiliary phase ~20 min with gadoxetate
Technique
  • Breath-hold sequences; respiratory triggering for some T2/DWI
  • In/opposed-phase T1 GRE (Dixon) for fat/iron and microscopic fat
  • Heavily T2 MRCP (thick-slab radial + thin 3D) BEFORE gadoxetate (contrast darkens biliary signal)
  • Dynamic fat-sat 3D T1 GRE pre and multiphase post-contrast
Series / Sequences
#Series / SequencePlaneWeighting / ReconThicknessNotes
1Ax T2 fat-sat (SSFSE/HASTE)axialT2 FS5-6 mmLesions, fluid
2Cor T2 (SSFSE)coronalT25-6 mmOverview, biliary
3Ax T1 in/opposed phase (Dixon)axialT1 GRE4-5 mmSteatosis, iron, adenoma
4Ax DWI/ADCaxialDWI5-6 mmb=50, 400-500, 800; lesion detection
5MRCP thick-slab radialcoronal obliqueHeavy T220-40 mm slabRadial projections; before contrast
6MRCP 3D respiratory-triggeredcoronalHeavy T2 (3D)1-1.5 mmThin source + MIP
7Ax 3D T1 GRE fat-sat preaxialT1 FS3-4 mmBaseline dynamic
8Ax 3D T1 dynamic post (arterial/PV/delayed)axialT1 FS +C3-4 mmMultiphase; bolus-tracked arterial
9Hepatobiliary phase (gadoxetate)axialT1 FS +C3-4 mm~20 min; lesion uptake, biliary excretion
Key points
  • Perform MRCP and any non-fat-sat T2 BEFORE gadoxetate—contrast in bile/excretion obscures MRCP.
  • Late arterial phase timing (bolus tracking/test bolus) is critical for HCC hypervascularity (LI-RADS).
  • In/opposed phase detects intracellular fat (steatosis, adenoma, AML) and iron.
  • Hepatobiliary phase (gadoxetate) aids FNH vs adenoma and small lesion/metastasis detection.
  • DWI improves lesion and small metastasis detection.
References
• ACR-SAR-SPR Practice Parameter for MRI of the Abdomen
• ACR LI-RADS CT/MRI Manual
• AJR: Gadoxetate Disodium-Enhanced MRI of the Liver (Part 1) link
• Radiopaedia: Liver MRI protocol / MRCP
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.