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Myelogram (Lumbar)

Fluoro+ ContrastNeuroverify
Indications
  • Spinal canal/nerve root compression when MRI contraindicated (pacemaker, hardware artifact) or inconclusive
  • CSF leak localization (often with CT myelogram)
  • Evaluation of arachnoiditis, spinal stenosis, disc herniation
  • Surgical planning, especially with extensive instrumentation
  • Assessment of nerve root avulsion
Patient prep
  • Review coagulation status; hold anticoagulants/antiplatelets per guidelines
  • Screen for contrast allergy and seizure-lowering meds (avoid drugs lowering seizure threshold)
  • Hydration before/after; consent
  • Check prior imaging; confirm level
Contrast
AgentNonionic water-soluble iodinated contrast approved for INTRATHECAL use ONLY (e.g., iohexol/Omnipaque intrathecal concentrations such as 180/240/300 labeled for myelography)
Routeintrathecal (subarachnoid) via lumbar puncture
DosePer label for lumbar myelography (typically ~10-15 mL of appropriate concentration; do not exceed labeled intrathecal dose)
TimingInject under fluoroscopy after confirming subarachnoid position; image immediately, then CT myelogram often follows
Technique
  • Position prone or lateral; sterile prep
  • Fluoroscopically guided lumbar puncture (commonly L2-L3 or L3-L4, below conus)
  • Confirm subarachnoid placement with free CSF return and a small test of contrast flowing freely in the thecal sac (not epidural/subdural)
  • Inject intrathecal contrast under fluoroscopy
  • Tilt table to distribute contrast to region of interest; obtain AP, lateral, and oblique spot films
  • Proceed to CT myelogram (post-myelography CT) for cross-sectional detail
Series / Sequences
#Series / SequencePlaneNotes
1Needle placement / test injectionLateral fluoroConfirm intrathecal (free contrast in thecal sac)
2AP lumbarAPNerve root sleeves, filling defects
3Lateral lumbarLateralCanal stenosis, disc impressions
4ObliqueRPO/LPONerve root cutoff, lateral recess
5Post-myelogram CTAxial CTCross-sectional detail, recommended adjunct
Key points
  • ONLY use contrast specifically labeled for intrathecal administration — inadvertent intrathecal injection of non-approved/ionic contrast can cause seizures, neurotoxicity, and death
  • Confirm subarachnoid (not subdural/epidural) placement before full injection
  • Keep head of bed elevated after procedure; avoid stooping; this reduces upward migration of contrast and post-procedure headache/seizure risk
  • Avoid drugs that lower seizure threshold (e.g., phenothiazines) periprocedurally
  • Watch for post-dural-puncture headache; hydration and rest
  • Contraindications: coagulopathy, infection at puncture site, raised ICP / posterior fossa mass (herniation risk)
References
• ACR–ASNR–SPR Practice Parameter for the Performance of Myelography and Cisternography (gravitas.acr.org/PPTS, DocId 64)
• ASNR Practice Guideline: Myelography — link
• Omnipaque (iohexol) intrathecal prescribing information (GE Healthcare)
• Radiopaedia: Myelography
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.