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Upper GI Series (UGI)

Fluoro+ ContrastAbdomen & Pelvisverify
Indications
  • Epigastric pain / dyspepsia
  • Suspected peptic ulcer disease
  • Gastric or duodenal mass/carcinoma
  • Gastric outlet obstruction
  • Postoperative evaluation (e.g., bariatric, fundoplication, gastrectomy — use water-soluble for leak)
  • Hiatal hernia / reflux
  • Unexplained nausea/vomiting
Patient prep
  • NPO at least 6-8 hours (NPO after midnight typical)
  • No smoking or gum chewing (increases secretions/motility)
  • Hold certain motility-altering meds per protocol
  • Remove abdominal radiopaque objects
Contrast
AgentHigh-density barium sulfate plus effervescent gas crystals for double-contrast; thin barium for single-contrast; water-soluble iodinated agent if leak/perforation or recent surgery
Routeoral
DoseEffervescent crystals (CO2) followed by high-density barium, then thin barium as needed
TimingReal-time fluoroscopy through esophagus, stomach, and duodenum
Technique
  • Optional glucagon IV (0.1-0.5 mg) to reduce peristalsis for double-contrast detail (if no contraindication)
  • Effervescent crystals then high-density barium; rotate patient to coat gastric mucosa
  • Double-contrast spot films of stomach in multiple obliquities (supine RPO/LPO, upright)
  • Prone/RAO single-contrast (full-column) compression views of antrum and duodenum
  • Image duodenal bulb and C-loop in multiple projections
  • Reflux and hiatal hernia maneuvers as for esophagram
Series / Sequences
#Series / SequencePlaneNotes
1Double-contrast stomachSupine + RPO/LPOMucosal relief, body and antrum
2Upright stomachUprightFundus, air-fluid level, GE junction
3Full-column antrum/duodenumProne RAOCompression of antrum and bulb
4Duodenal bulbRAO/supineUlcer, deformity
5Duodenal C-loop / sweepSupine + obliqueMass, annular pancreas, malrotation
6Esophagus screeningRAO/uprightOften included with UGI
Key points
  • Use water-soluble iodinated contrast for suspected perforation or postoperative leak; low-osmolar nonionic preferred if aspiration risk
  • Glucagon contraindicated in pheochromocytoma and insulinoma; use cautiously in diabetics
  • Double-contrast best for mucosal lesions; single-contrast/compression best for distensibility and motility
  • Effervescent agent contraindicated if obstruction or perforation suspected
  • Often combined with small bowel follow-through (UGI/SBFT)
References
• ACR Practice Parameter for the Performance of Esophagrams and Upper GI Examinations in Adults (gravitas.acr.org/PPTS)
• UT Southwestern Radiology Protocol: Upper GI Exam — Single or Double Contrast Barium
• Radiopaedia: Upper gastrointestinal series
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.