CTA GI Bleed (Active Gastrointestinal Hemorrhage)
CTA+ ContrastVascularAbdomen & Pelvis
Indications
- Overt GI bleeding (hematochezia, melena) — localize active hemorrhage
- Hemodynamically significant lower GI bleeding before embolization or surgery
- Obscure GI bleeding after negative or non-localizing endoscopy
- Suspected small bowel bleeding source
Patient prep
- NO oral contrast — positive oral contrast obscures intraluminal extravasation
- Large-bore IV (18 G preferred) for high flow rate
- Do not delay for renal function in hemodynamically significant bleeding; resuscitate concurrently
- Supine, arms up
Contrast
Agentiodinated (e.g. iohexol 350 or iopamidol 370)
RouteIV
Dose≈1.5 mL/kg (100-150 mL) at 4-5 mL/s with saline flush
TimingTriphasic: non-contrast, late arterial (bolus tracking in aorta, trigger ~150 HU), and delayed/venous ~90-150 s to confirm extravasation growth
Technique
- Supine, arms up; coverage diaphragm through symphysis pubis, identical range all phases
- Non-contrast first — identifies pre-existing intraluminal hyperdense material (pills, clips, prior contrast) that mimics bleeding
- Late arterial phase for active extravasation; delayed phase confirms (extravasated contrast pools/changes shape)
- 120 kV (100 kV thin patients); thin 1-1.25 mm recon; coronal reformats and thin-slab MIPs
- No oral or rectal contrast
Series / Sequences
| # | Series / Sequence | Plane | Thickness | Notes |
|---|---|---|---|---|
| 1 | Non-contrast axial | axial | 2.5-3 mm | Baseline intraluminal density |
| 2 | Arterial axial | axial | 1-3 mm | Active extravasation = new intraluminal contrast |
| 3 | Delayed/venous axial | axial | 2.5-3 mm | ~90-150 s; pooling/enlarging extravasation confirms active bleed |
| 4 | Coronal reformat + MIP | coronal | 2-3 mm / thin-slab MIP | Bowel survey, mesenteric vascular map for IR |
Key points
- Active bleeding = intraluminal contrast on arterial phase that is absent on non-contrast and changes/increases on delayed phase — all three phases matter
- CTA detects bleeding rates as low as ~0.3-0.5 mL/min and localizes for targeted angiography/embolization
- Never give positive oral contrast — it makes extravasation undetectable
- A negative CTA during a bleeding pause is common; consider repeat when bleeding recurs, or nuclear tagged-RBC scan for slower intermittent bleeding (see GI Bleed Tagged RBC protocol)
References
• ACR Appropriateness Criteria: Nonvariceal Upper Gastrointestinal Bleeding link
• ACR Appropriateness Criteria: Radiologic Management of Lower Gastrointestinal Tract Bleeding link
• RadioGraphics: CT for Evaluation of Acute Gastrointestinal Bleeding (Wells et al., 2018) link
• Radiopaedia: Gastrointestinal bleeding link
• ACR Appropriateness Criteria: Radiologic Management of Lower Gastrointestinal Tract Bleeding link
• RadioGraphics: CT for Evaluation of Acute Gastrointestinal Bleeding (Wells et al., 2018) link
• Radiopaedia: Gastrointestinal bleeding link
Source: Researched — verify against your institution
Reference template — verify and adapt to your scanner, vendor and institution before clinical use. Not a substitute for clinical judgment.